8 References

Anderson, Carl A, Fredrik H Pettersson, Geraldine M Clarke, Lon R Cardon, Andrew P Morris, and Krina T Zondervan. 2010. “Data Quality Control in Genetic Case-Control Association Studies.” Nature Protocols 5 (9): 1564.

Clayton, David G, Neil M Walker, Deborah J Smyth, Rebecca Pask, Jason D Cooper, Lisa M Maier, Luc J Smink, et al. 2005. “Population Structure, Differential Bias and Genomic Control in a Large-Scale, Case-Control Association Study.” Nature Genetics 37 (11): 1243.

Consortium, Wellcome Trust Case Control, and others. 2007. “Genome-Wide Association Study of 14,000 Cases of Seven Common Diseases and 3,000 Shared Controls.” Nature 447 (7145): 661.

Dudbridge, Frank. 2013. “Power and Predictive Accuracy of Polygenic Risk Scores.” PLoS Genetics 9 (3): e1003348.

González, Juan R, Josep L Carrasco, Frank Dudbridge, Lluı́s Armengol, Xavier Estivill, and Victor Moreno. 2008. “Maximizing Association Statistics over Genetic Models.” Genetic Epidemiology 32 (3): 246–54.

Lawrence, Michael, Wolfgang Huber, Hervé Pages, Patrick Aboyoun, Marc Carlson, Robert Gentleman, Martin T Morgan, and Vincent J Carey. 2013. “Software for Computing and Annotating Genomic Ranges.” PLoS Computational Biology 9 (8): e1003118.

MacArthur, Jacqueline, Emily Bowler, Maria Cerezo, Laurent Gil, Peggy Hall, Emma Hastings, Heather Junkins, et al. 2016. “The New NHGRI-EBI Catalog of Published Genome-Wide Association Studies (GWAS Catalog).” Nucleic Acids Research 45 (D1): D896–901.

Pe’er, Itsik, Roman Yelensky, David Altshuler, and Mark J Daly. 2008. “Estimation of the Multiple Testing Burden for Genomewide Association Studies of Nearly All Common Variants.” Genetic Epidemiology 32 (4): 381–85.

Price, Alkes L, Nick J Patterson, Robert M Plenge, Michael E Weinblatt, Nancy A Shadick, and David Reich. 2006. “Principal Components Analysis Corrects for Stratification in Genome-Wide Association Studies.” Nature Genetics 38 (8): 904.

Price, Alkes L, Noah A Zaitlen, David Reich, and Nick Patterson. 2010. “New Approaches to Population Stratification in Genome-Wide Association Studies.” Nature Reviews Genetics 11 (7): 459.

Purcell, Shaun, Benjamin Neale, Kathe Todd-Brown, Lori Thomas, Manuel AR Ferreira, David Bender, Julian Maller, et al. 2007. “PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses.” The American Journal of Human Genetics 81 (3): 559–75.

Silverberg, Mark S, Judy H Cho, John D Rioux, Dermot PB McGovern, Jing Wu, Vito Annese, Jean-Paul Achkar, et al. 2009. “Ulcerative Colitis–Risk Loci on Chromosomes 1p36 and 12q15 Found by Genome-Wide Association Study.” Nature Genetics 41 (2): 216.

Wigginton, Janis E, David J Cutler, and Gonçalo R Abecasis. 2005. “A Note on Exact Tests of Hardy-Weinberg Equilibrium.” The American Journal of Human Genetics 76 (5): 887–93.