All functions

checkForExpressionSet()

Check if object exists on the study server and if it's an ExpressionSet

.eafPlot()

Auxiliary function for eafPlot

.pzPlotgg()

Auxiliary function for pzPlot

ds.addPhenoData2eSet()

Add Phenotype data to ExpressionSet

ds.alleleFrequency()

Allelic frequency

ds.createRSE()

Create a RangedSummarizedExperiment from a RNAseq count table and a phenotypes table

ds.DESeq2()

Server-side Differential Gene Expression analysis using DESeq2

ds.edgeR()

Server-side Differential Expression Analysis using edgeR

ds.exactHWE()

Hardy-Weinberg Equilibrium testing

ds.fastGWAS()

Fast genome-wide association analysis (GWAS)

ds.featureData()

Retrieve information on features from eSets and RSEs.

ds.featureNames()

Retrieve feature names from eSets and RSEs.

ds.fvarLabels()

Retrieve phenotypic data (e.g. covariates) from eSets and RSEs.

ds.genoDimensions()

Get main dimensions of Genotype data

ds.GenotypeData()

Creates a GenotypeData object at each server

ds.getChromosomeNames()

Get names of chromosomes

ds.getSNPs()

Retrieve SNPs from

ds.getSNPSbyGen()

Subset GDS with gene(s)

ds.glmSNP()

Logistic regression analysis of pooled data for each SNP site in study

ds.index.gdsn()

Retrieve phenotypic data (e.g. covariates) from eSets.

ds.limma()

Server-side Differential Gene Expression analysis using limma

ds.lmFeature()

Linear regression analysis of pooled data for each CpG site in study

ds.make_valid_names()

Rename column names and character variables

ds.metaGWAS()

Genome-wide association analysis (GWAS)

ds.nFeatures()

Retrieve the number of features for eSets and RSEs.

ds.nSamples()

Retrieve the number of samples for eSets and RSEs.

ds.PCA()

Principal Component Analysis (PCA) on SNP genotype data

ds.PCASNPS()

Principal Component Analysis (PCA) on SNP genotype data

ds.PLINK()

Genome-wide association analysis (GWAS) using PLINK

ds.PRS()

Get Ploygenic Risk Score

ds.removeOutliers()

Filter potential CpG outliers

ds.RNAseqPreproc()

Filter Genes By Expression Level

ds.snptest()

Interface to run SNPtest commands on a ssh connection (with SNPtest 2.5.2 installed)

ds.subsetExpressionSet()

Subset ExpressionSet

ds.table_gds()

Contingency tables of phenotypes

ds.varLabels()

Retrieve phenotypic data (e.g. covariates) from eSets.

eafPlot()

EAF plot

get_EGA_url()

Get EGA URL

get_ga4gh_url()

Get GA4GH URL

glmSNP()

Fits a GLM to assess association between the outcome (binary variable) and a given SNP

lambdaNPlot()

Lambda-N plot

lmFeature()

Fits a LM to assess association between the features (outcome) and grouping variable (e.g case/control, condition, ...)

LocusZoom()

LocusZoom

manhattan()

Mannhattan Plot

metaBetaValues()

Meta-analysis of beta values

metaPvalues()

Meta-analysis of p-values

plot(<dsLmFeature>)

Generate a QQ-plot of p-values output from any omic data analysis

plotPCA()

Plot the results of a ds.PCA()

plotPCASNPS()

Plot the results of a ds.PCASNPS()

pzPlot()

P-Z plot

qqplot()

Create a quantile-quantile plot with ggplot2.

seNPlot()

SE-N Plot

standardizeGenoData()

Get standaridization coefficients of Genotype data

tolist()

PLINK arguments in the DataSHIELD required format