Fundamentals

NoteWhat You’ll Learn Here

Understanding the foundations of BigDataStatMeth is essential for working effectively with large-scale datasets. This section covers the core concepts that make scalable statistical computing possible.

1 Why These Fundamentals Matter

Modern genomic datasets routinely exceed available memory. BigDataStatMeth solves this challenge through intelligent design choices that let you work with data that would otherwise be impossible to analyze on standard workstations.

These fundamentals provide the practical knowledge you need to develop new statistical methods, optimize existing analyses, and understand why certain approaches work better than others at scale.


2 Core Concepts

TipThe Big Data Problem

Why do genomic datasets break traditional statistical software? What happens when your data exceeds available RAM?

Understanding these challenges is the first step toward solving them.

Explore the challenge →

WarningUnderstanding HDF5

The storage technology that makes working with large datasets practical. HDF5 provides random access to data subsets without loading entire files into memory.

Learn about HDF5 →

ImportantBlock-Wise Computing

The algorithmic strategy that makes large-scale analysis possible. Learn how to divide matrices into manageable pieces and process them efficiently.

Discover the algorithms →

CautionLinear Algebra Essentials

Matrix operations that form the foundation of statistical methods. Understand when to use each operation and how they work at scale.

Master the mathematics →


NoteReady to Apply These Concepts?

Once you understand these fundamentals, you’ll be ready to work through the Tutorials section or explore Practical Workflows to see complete analyses.